Novel microfluidic system and method for capturing cells

G - Physics – 01 – N

Patent

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Details

G01N 33/566 (2006.01) A61B 10/00 (2006.01) B01L 3/00 (2006.01) G01N 33/543 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2573044

The invention concerns a microfluidic device and its uses for capturing subset of cells in a biological fluid. Said device comprises a chamber (1) for circulating fluids whereof an inner wall (5) is provided with a covalent immobilization surface in the form of an organized self-assembled silane layer, whereto is fixed a layer of biomolecules for specific identification of the population of cells.

Dispositif microfluidique et ses applications pour la capture de sous- population de cellules au sein d'un fluide biologique. Le dit dispositif comporte une chambre (1) de circulation des fluides dont une paroi interne (5) est dotée d'un greffage par une couche de silane autoassemblée organisée, à laquelle est fixée une couche de biomolécules de reconnaissance spécifiques de la population de cellules.

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