Novel mixed lineage kinase (7) (mlk7) polypeptide,...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/54 (2006.01) A61K 31/00 (2006.01) A61K 31/7088 (2006.01) A61K 38/45 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) C07K 1/00 (2006.01) C07K 16/40 (2006.01) C12N 1/19 (2006.01) C12N 1/20 (2006.01) C12N 1/21 (2006.01) C12N 5/00 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12N 15/00 (2006.01) C12N 15/63 (2006.01) C12P 19/34 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2448102

The present invention provides isolated mixed lineage kinase (7) (MLK) polynucleotides, expression vectors, host cells, isolated polypeptides, methods of producing polypeptides, isolated antibodies, compositions having the foregoing, methods for identifying a compound that binds a polypeptide or polynucleotide, and to methods for identifying a compound that modulates the activity of a poypeptide.

La présente invention concerne des polynucléotides isolés de kinase 7 de lignée mélangée (MLK7), des vecteurs d'expression, des cellules hôtes, des polypeptides isolés, des méthodes de production de polypeptides, des anticorps isolés, des compositions contenant les éléments précités, des méthodes d'identification d'un composé liant un polypeptide ou un polynucléotide, ainsi que des méthodes d'identification d'un composé qui module l'activité d'un polypeptide.

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