C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/04 (2006.01) C07K 1/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12P 21/06 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2335585
Novel T110 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length T110 proteins, the invention further provides isolated T110 fusion proteins, antigenic peptides and anti-T110 antibodies. The invention also provides T110 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a T110 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
L'invention concerne de nouveaux polypeptides, de nouvelles protéines et molécules d'acide nucléique T110. Outre des protéines T110 isolées de longueur totale, l'invention concerne des protéines de fusion T110 isolées, des peptides antigéniques et des anticorps anti-T110. L'invention concerne également des molécules d'acide nucléique T110, des vecteurs d'expression recombinés contenant une molécule d'acide nucléique de l'invention, des cellules hôtes dans lesquelles on a introduit les vecteurs d'expression ainsi que des animaux transgéniques non humains dans lesquels on a introduit ou dissocié un gène T110. L'invention concerne également des méthodes diagnostiques, de criblage et thérapeutiques utilisant les compositions de l'invention.
Millennium Pharmaceuticals Inc.
Smart & Biggar
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