C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/04 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12N 15/28 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2323107
Novel T129 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length T129 proteins, the invention further provides isolated T129 fusion proteins, antigenic peptides and anti-T129 antibodies. The invention also provides T129 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a T129 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
L'invention porte sur de nouveaux polypeptides T129, de nouvelles protéines et molécules d'acide nucléique. L'invention porte non seulement sur des protéines T129 pleine longueur isolées, mais aussi sur des protéines de fusion T129 isolées, des peptides antigéniques et des anticorps anti-T129. L'invention porte en outre sur des molécules d'acide nucléique T129, des vecteurs d'expression de recombinaison contenant une molécule d'acide nucléique de l'invention, des cellules hôtes dans lesquelles ont été introduits les vecteurs d'expression et des animaux transgéniques dans lesquels un gène a été introduit ou coupé. Des procédés de diagnostic, dépistage et thérapeutiques sont également décrits.
Millennium Pharmaceuticals Inc.
Smart & Biggar
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