C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 337/00 (2006.01) A61K 31/38 (2006.01) C07D 337/08 (2006.01) C07D 409/12 (2006.01) C07D 487/08 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2464685
Mono-fluorinated and di-fluorinated benzothiepine apical sodium co-dependent bile acid transport (ASBT) inhibitors are disclosed together with methods of making the same, methods of using the same to treat hyperlipidemic conditions as well as pharmaceutical compositions containing the same compounds.
L'invention concerne des benzothiépines mono- et difluorées en tant qu'inhibiteurs du transport d'acides biliaires à co-dépendance sodique apicale (ASBT), des procédés de fabrication de ces benzothiépines, des méthodes d'utilisation de ces composés dans le traitement d'hyperlipidémies, ainsi que des compositions pharmaceutiques les contenant.
Koeller Kevin J.
Tremont Samuel J.
G.d. Searle Llc
Torys Llp
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