Novel monoclonal antibody for analyzing high-molecular...

C - Chemistry – Metallurgy – 07 – K

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Details

C07K 16/18 (2006.01) C12P 21/08 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/577 (2006.01) G01N 33/545 (2006.01)

Patent

CA 2760980

A monoclonal antibody that does not show a crossreactivity with middle-molecular weight (MMW) adiponectin and specifically reacts with high-molecular weight (HMW) adiponectin alone is disclosed. The monoclonal antibody of the present invention can be produced by using HMW adiponectin as an antigen. According to the monoclonal antibody of the present invention, a convenient, high-accurate, and versatile reagent for analyzing HMW adiponectin can be provided.

L'invention porte sur un anticorps monoclonal qui ne présente pas de réactivité croisée avec l'adiponectine de masse moléculaire moyenne (MMW) mais qui réagit spécifiquement avec l'adiponectine de masse moléculaire élevée (HMW) seule. Cet anticorps monoclonal peut être préparé en utilisant de l'adiponectine HMW en tant qu'antigène. A l'aide de l'anticorps monoclonal susdit, un réactif commode, de grande précision et polyvalent pour l'analyse de l'adiponectine HMW peut être fourni.

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