Novel mrthylenebisphosphonic acid derivatives

Details Novel mrthylenebisphosphonic acid derivatives Novel mrthylenebisphosphonic acid derivatives

C - Chemistry, Metallurgy

07

F

C07F 9/44 (2006.01) A61K 31/66 (2006.01) C07F 9/547 (2006.01) C07F 9/6533 (2006.01)

Patent

CA 2098734

2098734 9211268 PCTABS00014 The invention relates to novel methylenebisphosphonic acid ester amide derivatives of general formula (I), in which formula W1, W2, W3 and W4 are independently the group OR1 or the group NR2R3 wherein R1, R2 and R3 independently are hydrogen or straight or branched, optionally unsaturated C1-C22-alkyl, optionally substituted, optionally unsaturated C3-C10-cycloalkyl, aryl, aralkyl or silyl SiR3, or the groups R2 and R3 form together with the adjacent nitrogen atom a 3 to 10-membered saturated, partly saturated or aromatic heterocyclic ring, wherein in addition to the nitrogen atom, there may be one or two heteroatoms from the group N, O and S, provided that in formula (I) at least one of the groups W1, W2, W3 and W4 is hydroxy and at least one of the groups W1, W2, W3 and W4 is the amino group NR2R3, Q1 and Q2 are independently hydrogen, fluorine, chlorine, bromine or iodine, including the stereoisomers, such as the geometrical isomers and the optically active isomers, of the compounds, as well as the pharmacologically acceptable salts of the compounds.

Affiliated with

Also associated with

Rating

Novel mrthylenebisphosphonic acid derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel mrthylenebisphosphonic acid derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel mrthylenebisphosphonic acid derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1819092