Novel multifunctional cytokines

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 19/00 (2006.01) A61K 38/19 (2006.01) A61K 38/20 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01) C07K 14/54 (2006.01) C07K 14/55 (2006.01) C12N 7/00 (2006.01) C12N 15/24 (2006.01) C12N 15/62 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2678736

The present invention relates to a novel fusion protein with the formula X-Y, or Y- X, wherein X represents a first immunoregulating polypeptide and Y represents a second immunoregulating polypeptide different from X. The present invention also relates to a nucleic acid molecule encoding such a fusion protein and a vector comprising such a nucleic acid molecule. The present invention also provides infectious viral particles and host cells comprising such a nucleic acid molecule or such a vector as well as a process for producing such infectious viral particles. The present invention also relates to a method for recombinantly producing such a fusion protein. Finally, the present invention also provides a pharmaceutical composition comprising such a fusion protein, a nucleic acid molecule, a vector, infectious viral particles and a host cell as well as the therapeutic use thereof.

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