Novel, multiply substituted dtpa derivatives and their metal...

C - Chemistry – Metallurgy – 07 – F

Patent

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C07F 5/00 (2006.01) A61K 31/195 (2006.01) A61K 31/28 (2006.01) A61K 31/395 (2006.01) A61K 31/555 (2006.01) A61K 49/00 (2006.01) A61K 49/04 (2006.01) A61K 49/06 (2006.01) A61K 51/00 (2006.01) C07C 229/36 (2006.01) C07C 237/20 (2006.01) C07C 323/58 (2006.01) C07D 295/185 (2006.01) C07F 9/94 (2006.01) C07F 19/00 (2006.01)

Patent

CA 2206522

The invention concerns novel multiple-substituent diethylenetriamine pentaacetic acid derivatives, their complexes and complex salts, containing an element with the atomic numbers 20 - 32, 39 - 51 or 57 - 83, pharmaceutical compositions containing these compounds, methods of preparing the compounds, the use of the compositions as contrast media and antidotes, and methods of preparing the pharmaceutical compositions.

L'invention concerne de nouveaux dérivés substitués d'acide pentacétique de diéthylène triamine (DTPA), leurs complexes et sels complexes, contenant un élément ayant comme nombre atomique 20 - 32, 39 - 51 ou 57 - 83, des formulations pharmaceutiques contenant ces composés, des procédés pour les préparer, leur utilisation en tant qu'agents de contraste et antidote, et des procédés pour préparer ces formulations pharmaceutiques.

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