C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/10 (2006.01) A61K 31/40 (2006.01) A61K 31/4433 (2006.01) A61K 31/444 (2006.01) A61P 35/00 (2006.01) C07D 207/12 (2006.01) C07D 207/14 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 491/08 (2006.01)
Patent
CA 2724003
The present invention is directed to the compounds of formula (I), wherein R1 to R4 have the significances given herein, to processes for the manufacture of said compounds as well as medicaments containing said compounds. The compounds according to this invention show anti-proliferative and differentiation- inducing activity and are thus useful for the treatment of diseases such as cancer in humans or animals.
La présente invention concerne les composés de formule (I), dans laquelle R1 à R4 ont les significations données dans le présent document, des procédés de fabrication desdits composés, ainsi que des médicaments contenant lesdits composés. Les composés selon cette invention présentent une activité antiproliférative et inductrice de différenciation, et sont par conséquent utiles pour le traitement de maladies telles que le cancer chez les hommes ou les animaux.
Wong Jason Christopher
Wu Xihan
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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