Novel n-7-heterocyclyl pyrrolo[2,3-d]pyridines and their use

Details Novel n-7-heterocyclyl pyrrolo[2,3-d]pyridines and their use Novel n-7-heterocyclyl pyrrolo[2,3-d]pyridines and their use

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2249739

Described are pyrrolo[2,3-d]pyrimidines in which R1 to R5, m and n are as defined in the description. The compounds exhibit useful pharmaceutical properties and are particularly effective as protein tyrosine kinase inhibitors. The can be used to treat bone and other illnesses in warm-blooded animals in which inhibition of protein tyrosine kinase has a favourable effect.

L'invention concerne des pyrrolo[2,3-d]pyrimidines de formule (I), où R¿1?-R¿5?, m et n ont la signification indiquée dans la description. Ces composés présentent d'intéressantes propriétés pharmaceutiques et sont particulièrement efficaces en tant qu'inhibiteurs de la protéine tyrosine kinase. Ils peuvent être utilisés pour traiter les maladies osseuses ainsi que d'autres affections chez les animaux à sang chaud, sur lesquelles l'inhibition de la protéine tyrosine kinase a des effets favorables.

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