Novel n-aralkyl- and n-heteroaralkyl-aminoalkanephosphinic...

C - Chemistry – Metallurgy – 07 – F

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C07F 9/30 (2006.01) A61K 31/66 (2006.01) C07F 9/547 (2006.01) C07F 9/58 (2006.01) C07F 9/6518 (2006.01) C07F 9/6524 (2006.01) C07F 9/653 (2006.01)

Patent

CA 2095708

N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids of formula I Image wherein R is an aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, araliphatic or heteroarylaliphatic radical having at least 2 carbon atoms, R1 is hydrogen or hydroxy, R2 is an araliphatic or heteroarylaliphatic radical substituted by free or functionally modified carboxy that is bonded directly or by way of a spacer, and R3 is hydrogen, lower alkyl or a group R2, and the salts thereof have valuable nootropic and anti-epileptic properties and can be used in the preparation of a nootropic or anti-epileptic medicament.

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