C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 519/00 (2006.01) A61K 31/4545 (2006.01) A61P 31/04 (2006.01) C07D 309/40 (2006.01) C07D 491/056 (2006.01)
Patent
CA 2706929
Disclosed is 1-(2-(4-((2,3-dihydro(1,4)dioxino(2,3-c)pyridin-7- ylmethyl)amino)piperidin-1-yl)ethyl)-7-fluoro-1,5-naphthyridin-2(1H)-one monohydrate, which has strong antibacterial activity. The compound is highly safe and useful as an original drug for pharmaceutical preparations. Also disclosed is a method which is useful for producing 1-(2-(4-((2,3-dihydro(1,4)dioxino(2,3-c)pyridin-7-ylmethyl)amino)piperidin-1- yl)ethyl)-7-fluoro-1,5-naphthyridin-2(1H)-one monohydrate.
L'invention porte sur une 1-(2-(4-((2,3-dihydro(1,4)dioxino(2,3-c)pyridin-7-ylméthyl)amino)pipéridin-1-yl)éthyl)-7-fluoro-1,5-naphtyridin-2(1H)-one monohydratée, qui présente une grande activité antibactérienne. Le composé est hautement sûr et utile comme médicament initial pour des préparations pharmaceutiques. L'invention porte également sur un procédé qui est utile pour la fabrication de la 1-(2-(4-((2,3-dihydro(1,4)dioxino(2,3-c)pyridin-7-ylméthyl)amino)pipéridin-1-yl)éthyl)-7-fluoro-1,5-naphtyridin-2(1H)-one monohydratée.
Baba Yasutaka
Horikiri Hiromasa
Kiyoto Taro
Noguchi Toshiya
Syoji Muneo
Marks & Clerk
Taisho Pharmaceutical Co. Ltd.
Toyama Chemical Co. Ltd.
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