Novel neisseria meningitidis compounds and anti-infection...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/31 (2006.01) A61K 39/095 (2006.01) C07K 14/22 (2006.01) C07K 16/12 (2006.01) C12N 15/10 (2006.01) G01N 33/53 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2378875

The invention provides novel Neisseria meningitidis (Nm) polypeptides and polynucleotides which cover the Nm genetic diversity, and which correspond to polypeptide of Nm outer membrane and/or periplasma, and to methods for producing such Nm compounds. Also provided are anti-Nm infection, and particularly diagnostic, prophylactic and therapeutic uses thereof.

L'invention concerne des nouveaux polynucléotides et polypeptides de Neisseria meningitidis (Nm) couvrant la diversité génétique Nm et correspondant au polypeptide de la membrane externe et/ou du périplasme de Nm, ainsi que des méthodes de production de ces composés de Nm. L'invention concerne également des méthodes destinées à combattre les infections par Nm, et notamment des utilisations diagnostiques, prophylactiques et thérapeutiques desdits composés.

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