Novel neurotrophic factor protein and uses thereof

Details Novel neurotrophic factor protein and uses thereof Novel neurotrophic factor protein and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/475 (2006.01) A61K 38/18 (2006.01) C07K 16/22 (2006.01) C12N 15/12 (2006.01)

Patent

CA 2633468

The present invention discloses a novel neurotrophic factor protein, MANF2 and a genetic sequence encoding the same. The molecule will be useful in the development of a range of therapeutics and diagnostics useful in the treatment, prophylaxis and/or diagnosis of MANF2 dependent conditions. The molecule of the present invention is also a useful effector of primary and central neurons, especially dopaminergic neurons at the central nervous system and growth factor genes.

Cette invention concerne un nouveau facteur neurotrophique, MANF2, ainsi qu'une séquence génétique codant pour ce nouveau facteur neurotrophique. La molécule convient tout particulièrement à l'élaboration d'une gamme de médicaments et d'agents diagnostiques utilisés pour traiter, prévenir et/ou diagnostiquer des états dépendants du MANF2. La molécule décrite dans cette invention constitue également un effecteur utile des neurones primaires et des neurones centraux, en particulier, les neurones dopaminergiques au niveau du système nerveux central, et les gènes de facteurs de croissance.

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