Novel nimesulide compositions

A - Human Necessities – 61 – K

Patent

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A61K 9/14 (2006.01)

Patent

CA 2544404

The present invention provides nanoparticulate nimesulide compositions. The compositions preferably comprise nimesulide and at least one surface stabilizer adsorbed on or associated with the surface of the nimesulide particles. The nanoparticulate nimesulide particles preferably have an effective average particle size of less than about 2000 nm. The invention also provides methods of making and using nanoparticulate nimesulide compositions.

L'invention concerne des compositions de nimésulide en nanoparticules. Ces compositions contiennent, de préférence nimésulide et au moins un stabilisant de surface adsorbé par la surface des particules de nimésulide ou associé à ladite surface. Ces nanoparticules de nimésulide présentent, de préférence, une dimension de particule moyenne inférieure à 2000 nm. Elle concerne également des méthodes de préparation et d'utilisation de ces compositions de nimésulide en nanoparticules.

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