Novel nitrocatechol derivatives having selectin ligand activity

Details Novel nitrocatechol derivatives having selectin ligand activity Novel nitrocatechol derivatives having selectin ligand activity

A - Human Necessities

61

K

A61K 31/167 (2006.01) A61K 31/191 (2006.01) A61K 31/341 (2006.01) A61K 31/381 (2006.01) A61K 31/4418 (2006.01) A61K 31/4436 (2006.01) A61K 31/505 (2006.01) A61K 31/5377 (2006.01) A61P 1/00 (2006.01) A61P 11/00 (2006.01) A61P 17/00 (2006.01) A61P 17/06 (2006.01) A61P 29/00 (2006.01) A61P 43/00 (2006.01) C07D 213/30 (2006.01)

Patent

CA 2622935

Pharmaceutical compositions comprising at least one compound of e.g. the formulas (Ie) and a pharmaceutically acceptable carrier which is useful in a medicine wherein the symbols and substituents have the following meaning -X- is e.g. and Y is e.g. or the pharmaceutically acceptable salts, esters or amides and prodrugs of the above identified compounds can be applied to modulate the in- vitro and in- vivo binding processes mediated by E-, P- or L- selectin binding.

La présente invention concerne des compositions pharmaceutiques comprenant au moins un composé représenté par la formule (Ie), dans laquelle les symboles et les substituent ont la signification suivante X est ex. et Y est ex, et un excipient répondant aux normes pharmaceutiques qui convient dans un médicament, ou des sels, des esters ou des amides et des promédicaments répondant aux normes pharmaceutiques des composés susmentionnés qui peuvent être appliqués pour moduler des processus de fixation in vitro et in vivo induits par la fixation de la sélectine E-, P- ou L

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