C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/48 (2006.01) A61K 31/47 (2006.01) C07D 239/14 (2006.01) C07J 41/00 (2006.01) C07K 5/06 (2006.01) C12N 15/87 (2006.01)
Patent
CA 2324931
The invention concerns novel compounds useful as agents for transferring nucleic acids into cells. Said novel compounds are more particularly related to the lipopolyamine family, and comprise at least a cyclic amidine function. They are useful for transfecting nucleic acids of interest into different cell types, in vitro as well as in vivo or ex vivo.
La présente invention concerne de nouveaux composées utiles comme agents de transfert d'acides nucléiques dans les cellules. Ces nouveaux composés sont plus particulièrement apparentés à la famile des lipopolyamines, et comportent au moins une fonction amidine cyclique. Ils sont utiles pour la transfection des acides nucléiques d'intérêt dans différents types cellulaires, aussi bien in vitro que in vivo ou ex vivo.
Byk Gerardo
Frederic Marc
Hofland Hans
Scherman Daniel
Aventis Pharma S.a.
Robic
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