Novel nucleic acids and polypeptides related to a...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/54 (2006.01) A01K 67/027 (2006.01) C07K 16/40 (2006.01) C12N 9/10 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2323759

The present invention relates to a farnesyl-directed cysteine carboxymethyltransferase nucleic acid and polypeptide, especially one which is obtainable or derived from a human. The nucleic acid and polypeptide is useful in diagnostics and in assays for identifying agents which modulate signalling pathways, especially pathways involved in the cell cycle, cell proliferation, and cancer.

La présente invention porte sur un acide nucléique et un polypeptide apparentés à une carboxyméthyltransférase cystéine dirigée farnesyl qui peut être obtenue ou prélevée chez l'homme. L'acide nucléique et le polypeptide sont utilisés dans les diagnostiques et dans des dosages destinés à identifier des agents qui modulent les mécanismes de signalisation, notamment les mécanismes impliqués dans le cycle cellulaire, la prolifération cellulaire et le cancer.

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