Novel nucleic acids and proteins with p53 activity and...

Details Novel nucleic acids and proteins with p53 activity and... Novel nucleic acids and proteins with p53 activity and...

Category

C - Chemistry, Metallurgy

Subcategory

12

Subsubcategory

N

IPC codes

C12N 15/12 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) C07K 14/47 (2006.01) C12N 1/21 (2006.01)

Type

Patent

Patent number

CA 2372881

Description

The invention relates to novel p53 proteins with altered tetramerization domains (tet-p53) proteins and nucleic acids. The invention further relates to the use of the tet-p53 proteins in the treatment of p53 related disorders.

L'invention concerne de nouvelles protéines p53 comportant des domaines de tétramérisation (tet-p53) modifiés et de nouveaux acides nucléiques. L'invention concerne en outre l'utilisation des protéines tet-p53 dans le traitement de troubles associés aux p53.

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