C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2451058
HUMAN LGR9 GPCR polypeptides and related nucleic acids are provided. Included are natural HUMAN LGR9 GPCR homologs from several species and polypeptides comprising a HUMAN LGR9 GPCR domain having specific activity. The polypeptides may be produced recombinantly from transformed host cells with the subject nucleic acids. Also provided are 10 isolated hybridization probes and oligonucleotide primers capable of specifically hybridizing with the disclosed genes, specific binding agents and methods of making and using the subject compositions, including high throughput screens.
L'invention concerne des polypeptides GPCR LGR9 humains et des acides nucléiques apparentés. L'invention comprend en outre des homologues GPCR LGR9 humains issus de plusieurs espèces et des polypeptides comprenant un domaine de GCPR LGR9 humains, à activité spécifique. Ces polypeptides sont obtenus par recombinaison de cellules hôtes transformées avec les acides nucléiques objets. L'invention concerne par ailleurs des échantillons d'hybridation isolés et des oligonucléotides amorces, aptes à une hybridation spécifique avec les gènes décrits, des agents de liaison spécifiques et des procédés permettant de produire et d'utiliser les compositions en question, ainsi que des tris à rendement élevé.
Glass David J.
Murphy Andrew J.
Blake Cassels & Graydon Llp
Regeneron Pharmaceuticals Inc.
LandOfFree
Novel nucleic acids, polypeptides, methods of making, and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel nucleic acids, polypeptides, methods of making, and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel nucleic acids, polypeptides, methods of making, and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1972708