C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/09 (2006.01)
Patent
CA 2554707
Novel markers for prostate cancer that are both sensitive and accurate. Furthermore, these markers are able to distinguish between prostate cancer and benign prostate hyperplasia ("BPH"). These markers are overexpressed in prostate cancer specifically, as opposed to normal prostate tissue and/or BPH. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of prostate cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between prostate cancer and non-cancerous states.
Cette invention concerne des nouveaux marqueurs pour le cancer de la prostate qui sont à la fois sensibles et précis. De plus, ces marqueurs sont capables de distinguer un cancer de la prostate d'une hyperplasie prostatique bénigne. Lesdits marqueurs sont surexprimés spécifiquement dans le cancer de la prostates par opposition à des tissus prostatiques normaux et/ou une hyperplasie prostatique bénigne. La mesure de ces marqueurs, seuls ou en combinaison, dans des échantillons prélevés sur un patient donne des informations que le diagnosticien peut corréler avec un diagnostic probable de cancer de la prostate. Les marqueurs de la présente invention, seuls ou en combinaison, autorisent une détection différentielle poussée entre le cancer de la prostate et des états non cancéreux.
Akiva Pinchas
Ayalon-Soffer Michal
Dahary Dvir
Levine Zurit
Pollock Sarah
Borden Ladner Gervais Llp
Compugen Usa Inc.
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