C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/00 (2006.01) C07H 21/04 (2006.01) C07K 14/435 (2006.01) C07K 16/18 (2006.01) C12Q 1/04 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2555509
Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.
L'invention se rapporte à de nouveaux marqueurs sensibles et précis du cancer du poumon. Ces marqueurs sont particulièrement surexprimés dans le cancer du poumon, en comparaison au tissu pulmonaire normal. La mesure de ces marqueurs, seuls ou associés, dans des échantillons de patients, fournit des informations que le diagnosticien peut mettre en corrélation avec un diagnostic probable du cancer du poumon. Les marqueurs selon l'invention, seuls ou combinés, montrent un degré élevé de détection différentielle entre le cancer du poumon et des états non cancéreux.
Akiva Pinchas
Ayalon-Soffer Michal
Cojocaru Gad S.
Dahary Dvir
Diber Alexander
Borden Ladner Gervais Llp
Compugen Usa Inc.
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