Novel nucleotide and amino acid sequences, and assays and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2554623

Novel markers for colon cancer that are both sensitive and accurate. These markers are overexpressed in colon cancer specifically, as opposed to normal colon tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of colon cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between colon cancer and non-cancerous states.

La présente invention a trait à de nouveaux marqueurs qui sont à la fois sensibles et précis. Ces marqueurs sont surexprimés dans le cancer du côlon de manière spécifique, par opposition au tissu de côlon normal. La mesure de ces marqueurs, seuls ou en combinaison, dans des échantillons de patients fournit une information dont le diagnosticien peut établir la corrélation avec un diagnostic probable du cancer du côlon. Les marqueurs de la présente invention, seuls ou en combinaison, présentent un degré élevé de la détection différentielle entre des états de cancer du côlon et non cancéreux.

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