Novel nucleotide and amino acid sequences, and assays and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07H 21/00 (2006.01) C07K 14/435 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C07K 19/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2554440

Novel markers for breast cancer that are both sensitive and accurate. These markers are overexpressed in breast cancer specifically, as opposed to normal breast tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of breast cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between breast cancer and non-cancerous states.

La présente invention a trait à de nouveaux marqueurs pour le cancer du sein qui sont à la fois sensibles et précis. Ces marqueurs sont surexprimés dans le cancer du sein spécifiquement, par opposition au tissu de sein normal. La mesure de ces marqueurs, seuls ou en combinaison, dans des échantillons de patientes fournit une information dont le diagnosticien peut établir la corrélation avec un diagnostic probable du cancer du sein. Les marqueurs de la présente invention, seuls ou en combinaison, présentent un degré élevé de détection différentielle entre des états de cancer du sein et non cancéreux.

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