Novel oligosaccharide derivatives, preparation method...

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 21/00 (2006.01) A61K 47/48 (2006.01) C07H 3/06 (2006.01) C07H 15/12 (2006.01) C07H 19/04 (2006.01) C07H 19/044 (2006.01) C07H 19/048 (2006.01) C07K 17/10 (2006.01) C12N 9/96 (2006.01)

Patent

CA 2192073

Compounds including one or more oligosaccharides each of which is covalently bonded to one or more, particularly one, two or three, molecules, matrices or particles, by means of an intermediate molecule having a nitrogen atom on an alpha carbon of a C=O group and one or more, particularly one, two or three, functional groups, the covalent bond between said intermediate molecule and the oligosaccharide being via said nitrogen atom, and the covalent bond between said intermediate molecule and said molecule(s), matrix(-ces) or particle(s) being via said functional group(s) of said intermediate molecule and suitable functional groups on said molecule(s), matrix(-ces) or particle(s).

L'invention a pour objet des composés comprenant un ou plusieurs oligosides, chacun desdits oligosides étant fixé de façon covalente sur une ou plusieurs molécules, matrices ou particules, en particulier une, deux ou trois, grâce à une molécule intermédiaire possédant un atome d'azote porté par un carbone en a d'un groupe C = O et un ou plusieurs groupes fonctionnels, en particulier un, deux ou trois, la liaison covalente entre ladite molécule intermédiaire et l'oligoside ayant lieu par l'intermédiaire du susdit atome d'azote, et la liaison covalente entre ladite molécule intermédiaire et la susdite molécule, la susdite matrice, la susdite particule, ou les susdites molécules, les susdites matrices, les susdites particules ayant lieu par l'intermédiaire du ou des susdits groupes fonctionnels de ladite molécule intermédiaire et des groupes fonctionnels appropriés sur la (les) molécule(s), la (les) matrice(s) ou la (les) particule(s).

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