Novel oncogene nrf2

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2726691

The present invention provides a marker which can be used as an indicator for efficacy prediction of an mTOR re-lated anticancer agent or prognostic prediction, and a novel anticancer agent The present invention provides a method for efficacy evaluation of a cancer drug, and, specifically, a prediction method for the efficacy of an mTOR-related cancer drug by detecting NRF2 abnormality In addition, the present invention provides a prognostic prediction method for cancer, and, specifically, a pre-diction method for the prognosis of cancer by detecting NRF2 abnormality Furthermore, the present invention provides a novel anticancer agent that targets NRF2

La présente invention concerne un marqueur qui peut être utilisé en tant quindicateur pour la prédiction defficacité dun agent anticancéreux associé à mTOR ou la prédiction pronostique, et un nouvel agent anticancéreux. La présente invention concerne un procédé pour lévaluation de lefficacité dun médicament anticancéreux et, spécifiquement, un procédé de prédiction pour lefficacité dun médicament anticancéreux associé à mTOR par détection dune anomalie de NRF2. De plus, la présente invention concerne un procédé de prédiction pronostique pour le cancer, et, spécifiquement, un procédé de prédiction pour le pronostic du cancer par détection dune anomalie de NRF2. De plus, la présente invention concerne un nouvel agent anticancéreux qui cible NRF2.

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