Novel ortho-aminoanilides for the treatment of cancer

Details Novel ortho-aminoanilides for the treatment of cancer Novel ortho-aminoanilides for the treatment of cancer

C - Chemistry, Metallurgy

07

D

C07D 265/34 (2006.01) A61K 31/40 (2006.01) A61K 31/535 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01) C07D 207/06 (2006.01) C07D 207/12 (2006.01) C07D 211/42 (2006.01) C07D 265/30 (2006.01) C07D 413/06 (2006.01)

Patent

CA 2734349

The present invention is directed to the compounds of formula (I), wherein R1 to R5 have the significances given herein, to processes for the manufacture of said compounds as well as medicaments containing said compounds. The compounds according to this invention show anti-proliferative and differentiation- inducing activity and are thus useful for the treatment of diseases such as cancer in humans or animals.

La présente invention concerne des composés de formule (I), dans laquelle R1 à R5 ont les significations données ici, des procédés pour la fabrication desdits composés ainsi que des médicaments contenant lesdits composés. Les composés selon cette invention présentent une activité antiproliférative et induisant la différenciation et sont donc utiles pour le traitement de maladies comme le cancer chez l'homme ou l'animal.

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