Novel oxadiazole derivatives and their use as positive...

C - Chemistry – Metallurgy – 07 – D

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C07D 413/04 (2006.01) A61K 31/4245 (2006.01) A61P 25/00 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2608012

The present invention relates to new compounds which are Oxadiazole derivatives of formula (I) wherein B, P, Q,W, R1 and R2 are defined in the description. Invention compounds are useful in the prevention or treatment of central or peripheral nervous system disorders as well as other disorders modulated by mGluR5 receptors.

La présente invention concerne de nouveaux composés qui sont des dérivés d'oxadiazole représentés par la formule générale (I). Dans cette formule, B, P, Q, W, R1 et R2 désignent des éléments définis dans la description. Ces composés sont utiles pour le traitement ou la prévention de troubles du système nerveux central ou périphérique ainsi que d'autres troubles modulés par les récepteurs mGluR5.

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