Novel oxadiazole derivatives and thiadiazole derivatives...

Details Novel oxadiazole derivatives and thiadiazole derivatives... Novel oxadiazole derivatives and thiadiazole derivatives...

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 27/02 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2676163

Compounds represented by the general formula (I) or salts thereof: (I) wherein A is a benzene ring, a thiophene ring, or a pyridine ring; Ra is hydrogen, halogeno, alkyl, or alkoxy; B is a pyridine ring, a pyrimidine ring, or a quinoline ring; C is a benzene ring, a pyridine ring, a quinoline ring, or an isoquinoline ring; X and Y may be the same or different and are each oxygen or sulfur (with the proviso that a case wherein X is sulfur and Y is oxygen is excepted); R1 is hydrogen, halogeno, amino, cycloalkylamino, alkylcarbonylamino, alkyloxycarbonylamino, alkylamino- carbonyl, or a nonaromatic heterocyclic group; and R2 and R2' may be the same or different and are each hydrogen, halogeno, alkyl, halogenoalkyl, or halogenoalkoxy.

L'invention concerne des composés représentés par la formule générale (I) ou des sels de ceux-ci. Dans cette formule, A représente un noyau benzène, un noyau thiophène ou un noyau pyridine; Ra représente hydrogène, halogéno, alkyle ou alcoxy; B représente un noyau pyridine,un noyau pyrimidine ou un noyau quinoline; C représente un noyau benzène, un noyau pyridine, un noyau quinoline ou un noyau isoquinoline; X et Y peuvent être différents ou identiques et représentent chacun oxygène ou souffre (à condition que, dans ce cas excepté, X représente souffre et Y oxygène); R1 représente hydrogène, halogéno, amino, cycloalkylamino, alkylcarbonylamino, alkyloxycarbonylamino, alkylamino- carbonyle ou un groupe non aromatique hétérocyclique; et R2 et R2' peuvent être identiques ou différents et représentent chacun hydrogène, halogéno, alkyle, halogénoalkyle ou halogénoalcoxy.

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