Novel oxazolidinone derivatives and a process for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 413/14 (2006.01) C07D 413/08 (2006.01) C07D 413/10 (2006.01)

Patent

CA 2411859

The present invention relates to novel oxazolidinone derivatives, their pharmaceutically acceptable salts and a process for the preparation thereof. More particularly, the present invention relates to oxazolidinone derivatives having pyridine or pyrimidine moeity substituted by heterocycle and heteroaromaticcycle at 4-position of phenyl ring. The compounds of the present invention have wide antibacterial spectrum, superior antibacterial activity and low toxicity, such that the compound of this invention can be used as an antibacterial agent.

La présente invention concerne de nouveaux dérivés oxazolidinine, les sels pharmaceutiquement acceptables de ces dérivés et un processus de préparation de ceux-ci. Cette invention concerne plus particulièrement des dérivés oxazolidinine possédant une fraction pyridine ou pyrimidine substituée par hétérocycle et hétérocycle aromatique en position 4 du noyau phényle. Les composés de cette invention possèdent un large spectre antibactérien, une activité antibactérienne supérieure et une faible toxicité, de sorte que ce composé convient comme agent antibactérien.

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