A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2332545
This invention provides vehicles capable of delivering high concentrations of poorly hydrophilic/poorly lipophilic compounds to animals, by combining compounds having biocompatible hydrophobic domains with conjugates having both hydrophobic and hydrophilic regions. Such formulations are suitable for a number of uses in animals, particularly the administration thereto of high concentrations of therapeutically useful compound, without an undue level of side effects.
La présente invention concerne des véhicules capables de délivrer à des animaux des concentrations élevées de composés faiblement hydrophiles et faiblement lipophiles, au moyen d'une combinaison de composés possédant des domaines hydrophobes biocompatibles avec des conjugués qui possèdent à la fois des régions hydrophobes et hydrophiles. De telles formulations conviennent dans un certain nombre d'utilisations chez des animaux, en particulier pour l'administration de concentrations élevées de composés thérapeutiquement utiles, sans effets secondaires de niveau inacceptable.
Ahmad Imran
Ali Shaukat
Hirsh Donald
Janoff Andrew
Li Xingong
Osler Hoskin & Harcourt Llp
The Liposome Company Inc.
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