C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/08 (2006.01) A61K 39/395 (2006.01) A61P 37/08 (2006.01) C07K 16/42 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/13 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2396889
A novel peptide; a screening method by using this peptide; and an antibody obtained by this screening method. A novel peptide consisting of 18 amino acids represented by SEQ ID NO:1 in Sequence Listing; a method of screening human type antihuman IgE monoclonal antibody by using this peptide; and human type antihuman IgE monoclonal antibody obtained by this screening method. The antibody thus obtained is useful as a preventive and/or a remedy for allergic diseases.
L'invention concerne un nouveau peptide, un procédé de criblage utilisant ledit peptide, et un anticorps obtenu par ledit procédé de criblage. L'invention concerne, en particulier, un nouveau peptide constitué de 18 acides aminés et représenté par SEQ ID NO:1 dans la liste des séquences, un procédé de criblage d'un anticorps monoclonal de type humain dirigé contre les IgE humaines utilisant ledit peptide, et un anticorps monoclonal de type humain dirigé contre les IgE humaines obtenu par ledit procédé de criblage. L'anticorps ainsi obtenu est utilisé comme agent prophylactique et/ou thérapeutique pour les maladies allergiques.
Fujise Nobuaki
Kuriyama Masayoshi
Satake Toshiko
Takahashi Ken
Tanaka Hideki
Daiichi Pharmaceutical Co. Ltd.
Dennison Associates
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