Novel peptide inhibitors of hepatitis c virus replication

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 217/26 (2006.01) A61K 31/16 (2006.01) A61P 31/14 (2006.01) C07D 401/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2686546

The embodiments provide compounds of the general Formula (I), as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments provide compounds of the general Formula (II), as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.

L'invention concerne des composés de la formule générale (I), ainsi que des compositions, y compris des compositions pharmaceutiques, comprenant un composé de l'invention. L'invention concerne des composés de la formule générale (II), ainsi que des compostions, incluant des compositions pharmaceutiques, comprenant un composé de l'invention. L'invention concerne en outre des procédés de traitement, y compris des procédés de traitement d'une infection par le virus de l'hépatite C et des procédés de traitement de la fibrose du foie, les procédés impliquant généralement l'administration à un individu qui en a besoin d'une quantité efficace d'un composé ou d'une composition de l'invention.

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