Novel peptides

Details Novel peptides Novel peptides

C - Chemistry, Metallurgy

07

K

C07K 14/60 (2006.01) C07K 14/575 (2006.01) C12N 15/16 (2006.01)

Patent

CA 2696819

The present invention provides a novel peptide-type compound which induces secretion of growth hormone and which has the activity of increasing the intracellular calcium ion concentration, wherein at least one amino acid is replaced by a modified amino acid and/or a non-amino acid compound, or a pharmaceutically acceptable salt thereof. Specifically, this invention relates to a peptide-type compound, (a) which comprises one amino acid sequence selected from the group consisting of the amino acid sequences set forth in SEQ ID NOS: 1, 2, 3, 8, 9, 10, 11, 16, 17, 22, 25, 26, 27, 28, 29, 30 and 31, or an amino acid sequence thereof wherein one to several amino acids may be deleted, replaced and/or added, and (b) which has an activity of increasing the intracellular calcium ion concentration, or a pharmaceutically acceptable salt thereof. This invention also relates to a DNA coding for the amino acid sequence of the peptide-type compound.

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