Novel peptides and remedy for bone diseases containing the...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61K 38/23 (2006.01) A61P 19/10 (2006.01) C07K 14/72 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2216704

A new substance useful as a drug for the treatment of osteopathy is disclosed. The present invention provides a peptide and derivative thereof, said peptide having an amino acid sequence designated hereunder as follows, wherein both of the peptide and derivative thereof having growth promotion effects and activity promotion effects on osteoblasts, as well as a drug having the peptide as an effective component for the treatment of osteopathy. Lys Leu Thr Thr Ile Phe Pro Leu Asn Trp Lys Tyr Arg Lys Ala Leu 1 5 10 15

Cette invention concerne de nouvelles substances pouvant être utilisées comme médicaments contre les maladies osseuses. Cette invention concerne un peptide dont la séquence d'acides aminés correspond à la formule (I), des peptides dérivés de ce peptide qui ont pour effet de favoriser la multiplication d'ostéoblastes et d'en accroître l'activité, et, enfin, un médicament contre les maladies osseuses contenant un tel peptide en qualité d'ingrédient actif.

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