C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61P 31/00 (2006.01) A61P 33/00 (2006.01) A61P 37/02 (2006.01) C07K 16/00 (2006.01) C12N 1/21 (2006.01) C12N 9/48 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12Q 1/37 (2006.01)
Patent
CA 2625183
In one aspect, the present invention provides isolated novel peptides that can be used to modulate innate immunity in a subject, and/or for the treatment of an immune-related disorder, including treating and preventing infection by modulating innate immunity. Also provided are an agent reactive with the peptide, a pharmaceutical composition that includes the peptide, an isolated nucleic acid molecule encoding the peptide, a recombinant nucleic acid construct that includes the nucleic acid molecule, at least one host cell comprising the recombinant nucleic acid construct, and a method of producing the peptide using the host cell. The present invention further provides a method for treating and/or preventing infection in a subject by administering the peptide of the invention to the subject, thereby modulating innate immunity in the subject. Additionally, the present invention provides a method for predicting whether a subject would be responsive to treatment with a peptide of the invention.
Selon un aspect, la présente invention concerne de nouveaux peptides isolés permettant de moduler l'immunité innée d'un patient et/ou de traiter un trouble lié à l'immunité, y compris de traiter et de prévenir l'infection par modulation de l'immunité innée. L'invention concerne également un agent réagissant avec le peptide, une composition pharmaceutique contenant ce peptide, une molécule d'acide nucléique isolée codante pour le peptide, une construction d'acide nucléique recombinante contenant la molécule d'acide nucléique, au moins une cellule hôte contenant la construction d'acide nucléique recombinante. L'invention concerne également un procédé de production du peptide à l'aide de la cellule hôte. En outre, la présente invention concerne un procédé de traitement et/ou de prévention de l'infection chez un patient par administration du peptide selon l'invention au patient, ce qui permet de moduler l'immunité innée du patient. En plus, la présente invention concerne un procédé permettant de prédire si un patient sera sensible au traitement par un peptide selon l'invention.
Donini Oreola
Lentz Shannon Wayne
Rozek Annett
Inimex Pharmaceuticals Inc.
Mccarthy Tetrault Llp
LandOfFree
Novel peptides for treating and preventing immune-related... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel peptides for treating and preventing immune-related..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel peptides for treating and preventing immune-related... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1714479