Novel peptides for use in immunotherapy of autoimmune diseases

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2334947

The invention relates to the use of novel peptides in a peptide induced tolerance therapy to prevent autoimmune disorders and in particular their use in treatment of chronic destruction of articular cartilage. The invention furthermore embraces pharmaceutical compositions comprising said peptides and a diagnostic method for the detection of autoreactive T cells in a test sample.

L'invention se rapporte à l'utilisation de nouveaux peptides dans une thérapie consistant à induire une tolérance au moyen de peptides dans le but de prévenir des affections auto-immunes et à l'utilisation de ces peptides pour traiter la destruction chronique du cartilage articulaire. L'invention se rapporte également à des compositions pharmaceutiques comportant de tels peptides et à une méthode diagnostique pour la détection de lymphocytes T autoréactifs dans un échantillon d'essai.

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