Novel peptides which inhibit complement activation

Details Novel peptides which inhibit complement activation Novel peptides which inhibit complement activation

C - Chemistry, Metallurgy

07

K

C07K 14/00 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61L 27/00 (2006.01) A61M 1/38 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2248772

Peptides capable of inhibiting complement activation are provided. Methods of inhibiting complement activation and complement- mediated tissue injury using these peptides are also provided. In addition, a method of producing compositions capable of inhibiting complement activation using these peptides is provided, along with the peptide analogs and peptidomimetics produced by the method.

On décrit des peptides pouvant inhiber l'activation du complément, de même que des procédés destinés à inhiber cette activation ainsi que les lésions tissulaires induites par ce complément, et dans lesquels on utilise de tels peptides. En outre, on décrit un procédé de production de compositions pouvant inhiber l'activation du complément au moyen de ces peptides, de même que des analogues peptidiques et des peptidomimétiques obtenus à l'aide de ce procédé.

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