Novel pharmaceutical compositions comprising agonists of the...

A - Human Necessities – 61 – K

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A61K 31/191 (2006.01) A61K 31/18 (2006.01) C07D 235/02 (2006.01) C07D 307/02 (2006.01) C07D 311/08 (2006.01) C07D 311/10 (2006.01) C07D 311/14 (2006.01) C12Q 1/68 (2006.01) G01N 33/78 (2006.01)

Patent

CA 2560526

The invention provides compounds of formula I or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition mediated by a thyroid receptor. Formula (I) wherein R1, R2, n, Y, Y', R3, R4, W and R5 are as defined in the specification.

La présente invention concerne des composés de formule (I) ou un ester, amide, solvate ou sel de ceux-ci, y compris un sel d'un ester ou amide de ceux-ci, et un solvate d'un ester, amide ou sel de ceux-ci, acceptable d'un point de vue pharmaceutique. L'invention a également pour objet l'utilisation de ces composés pour traiter ou prévenir un état pathologique lié au récepteur de la thyroïde. Dans la formule (I), R?1¿, R?2¿, n, Y, Y', R?3¿, R?4¿, W et R?5¿ sont tels que définis dans la spécification.

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