Novel phencyclidine derivatives, preparation methods and...

Details Novel phencyclidine derivatives, preparation methods and... Novel phencyclidine derivatives, preparation methods and...

C - Chemistry, Metallurgy

07

D

C07D 409/04 (2006.01) A61K 31/38 (2006.01) A61K 31/445 (2006.01) C07D 333/20 (2006.01) C07D 405/06 (2006.01) C07D 405/08 (2006.01) C07D 405/14 (2006.01) C07D 409/06 (2006.01) C07D 409/08 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2292642

The invention concerns novel phenycyclidine derivatives with selective affinity for low affinity receptors, methods for preparing them, pharmaceutical compositions containing them and their use as protective agents for central or peripheral nervous system cells against acute or chronic degeneration, or as anticonvulsant.

La présente invention concerne de nouveaux dérivés de phencyclidines possédant une affinité sélective pour les récepteurs de basse affinité, des procédés pour leur préparation, des compositions pharmaceutiques les contenant et leur utilisation notamment en tant qu'agent protecteur des cellules du système nerveux central ou périphérique contre les dégénérescences aiguës ou chroniques, ou comme agent anticonvulsivant.

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