C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/81 (2006.01) A61K 31/455 (2006.01) C07D 209/08 (2006.01) C07D 213/82 (2006.01) C07D 215/08 (2006.01) C07D 215/18 (2006.01) C07D 241/42 (2006.01) C07D 265/36 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2741153
This invention relates to novel phenyl amide or pyridyl amide derivatives of the formula (I) wherein A1, A2, B1, B2 and R1 to R11 are as defined in the description and in the claims, as well as pharma-ceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medica-ments for the treatment of diseases such as type II di-abetes.
La présente invention concerne des nouveaux dérivés de d'amides phényliques ou d'amides pyridyliques de formule (I), dans laquelle A1, A2, B1, B2 et R1 to R11 sont tels que définis dans la description et les revendications, ainsi que leurs sels pharmaceutiquement acceptables. Ces composés sont des agonistes de GPBAR1 et peuvent être utilisés comme médicaments pour le traitement de maladies telles que le diabète de type 2.
Bissantz Caterina
Dehmlow Henrietta
Martin Rainer E.
Obst Sander Ulrike
Richter Hans
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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