Novel phloroglucinol derivatives having selectin ligand...

A - Human Necessities – 61 – K

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A61K 31/167 (2006.01) A61K 31/191 (2006.01) A61K 31/341 (2006.01) A61K 31/381 (2006.01) A61K 31/4418 (2006.01) A61K 31/4436 (2006.01) A61K 31/505 (2006.01) A61K 31/5377 (2006.01) C07D 213/30 (2006.01) C07D 213/40 (2006.01) C07D 213/75 (2006.01) C07D 239/20 (2006.01) C07D 307/68 (2006.01) C07D 333/24 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2622467

Pharmaceutical compositions comprising at least one compound of the formula (I) and a pharmaceutically acceptable carrier which is useful in a medicine wherein the symbols and substituents have the following meaning -X- is e.g. and Y being e.g. or the pharmaceutically acceptable salts, esters or amides and prodrugs can be applied to modulate the in-vitro and in-vivo binding processes mediated by E-, P- or L-selectin binding.

La présente invention concerne des compositions pharmaceutiques comprenant au moins un composé représenté par la formule (I), dans laquelle les symboles et les substituent ont la signification suivante X est ex. et Y est ex, et un excipient répondant aux normes pharmaceutiques qui convient dans un médicament, ou des sels, des esters ou des amides et des promédicaments répondant aux normes pharmaceutiques qui peuvent être appliqués pour moduler des processus de fixation in vitro et in vivo induits par la fixation de la sélectine E-, P- ou L

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