Novel phosphorus-containing prodrugs

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 9/6584 (2006.01)

Patent

CA 2362805

Novel cyclic phosphoramidate prodrugs of drugs of formula (I) of parent drugs MH their use in delivery of drugs to the liver, their use in enhancing oral bioavailability, and their method of preparation are described.

L'invention concerne des nouveaux promédicaments phosphoramidates cycliques de médicaments de formule (I), leur utilisation dans la libération de médicaments dans le foie, leur utilisation pour améliorer la biodisponibilité orale, et les méthodes pour les préparer.

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