Novel phosphorylated sequences of phosphatase cdc25b,...

C - Chemistry – Metallurgy – 07 – K

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Details

C07K 7/08 (2006.01) A61K 39/395 (2006.01) C12N 9/16 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2559124

The invention relates to a peptide sequence which is characterised in that it comprises or is formed by a fragment of at least approximately 10 amino acids from the following sequence SEQ ID NO: 1: LRNITNS¿p?QAPDGRRKSEAGSG SEQ ID NO: 1, wherein the serine residue at position 7 is phosphorylated, said fragment containing the phosphorylated serine residue. The invention also relates to a polyclonal or monoclonal antibody that can recognise a peptide sequence as defined above.

La présente invention concerne une séquence peptidique caractérisée en ce qu'elle comprend ou est constituée par un fragment d'au moins environ 10 acides aminés issus de la séquence SEQ ID NO : 1 suivante : LRNITNSpQAPDGRRKSEAGSG SEQ ID NO : 1 dans laquelle le résidu sérine en position 7 est phosphorylé, ledit fragment susmentionné contenant ledit résidu sérine phosphorylé. La présente invention concerne également un anticorps polyclonal ou monoclonal susceptible de reconnaître une séquence peptidique telle que définie ci-dessus.

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