Novel phosphorylated sequences of the phosphatase cdc25b,...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/16 (2006.01) A61K 38/43 (2006.01) A61P 35/00 (2006.01) C07K 16/40 (2006.01) G01N 33/543 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2528844

The invention relates to a peptide sequence characterised in comprising, or being made from a fragment of at least two amino acids from the following sequence SEQ ID NO: 1: TPVQNKRRRS¿p?VTPPEEQQE SEQ ID NO: 1 in which the serine residue in position 10 is phosphorylated, the above fragment containing said phosphorylated serine residue. The invention further relates to a polyclonal or monoclonal antibody for recognition of a peptide sequence as above.

La présente invention concerne une séquence peptidique caractérisée en ce qu'elle comprend ou est constituée par un fragment d'au moins environ 10 acides aminés issus de la séquence SEQ ID NO : 1 suivante : TPVQNKRRRSpVTPPEEQQE SEQ ID NO : 1 dans laquelle le résidu sérine en position 10 est phosphorylé, ledit fragment susmentionné contenant ledit résidu sérine phosphorylé. La présente invention concerne également un anticorps polyclonal ou monoclonal susceptible de reconnaître une séquence peptidique telle que définie ci-dessus.

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