Novel physiologically active substance, process for...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61P 9/00 (2006.01) A61P 13/00 (2006.01) A61P 25/00 (2006.01) A61P 27/00 (2006.01) C07K 14/46 (2006.01) C07K 14/575 (2006.01) C07K 16/18 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2352760

A novel peptide recognized as a ligand by a G protein-coupled receptor protein. The above peptide is usable in: (1) developing a receptor-bonded assay system and screening a candidate compound for a drug with the use of a recombinant receptor protein expression system; and (2) developing drugs such as a central function controlling agent, a circulatory function controlling agent, a heart function controlling agent, an immunological function controlling agent, a digestive function controlling agent, a metabolic function controlling agent or a genital function controlling agent.

L'invention porte sur un nouveau peptide reconnu comme un ligand par une protéine réceptrice couplée à une protéine G. Le susdit peptide peut servir: (1) à développer un système d'essai lié à un récepteur, et à cribler un composé candidat d'un médicament avec l'aide d'un système d'expression d'une protéine réceptrice de recombinaison; (2) à développer des médicaments tels qu'un agent régulateur des fonctions centrales, un agent régulateur des fonctions circulatoires, un agent régulateur des fonctions cardiaques, un agent régulateur des fonctions immunologiques, un agent régulateur des fonctions digestives, un agent régulateur des fonctions métaboliques, et un agent régulateur des fonctions génitales.

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