Novel pilocarpine derivatives and process for their preparation

Details Novel pilocarpine derivatives and process for their preparation Novel pilocarpine derivatives and process for their preparation

C - Chemistry, Metallurgy

07

D

C07D 233/64 (2006.01) A61K 31/415 (2006.01) C07D 233/54 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2096444

2096444 9209583 PCTABS00013 The object of the invention are novel bispilocarpates useful in the treatment of glaucoma and having general formula (I), wherein A) Y is hydrogen or the acyl group (II), and W is the group -O-A-O-Z-Y', wherein Y' is hydrogen or the acyl group (III), the groups R and R' having different meanings and may be the same or different and A is an aliphatic or aromatic bridging group, and -Z-Y' is (IV), or B) W is OR, wherein R has the same meaning as above, Y is (V), where R' has the same meaning as above, B means the same as A and Z'-OR' is (VI) or C) W and Y together mean -A-O-Z-C-B-C-, where the symbols have the same meanings as above.

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