Novel piperazinone derivates for the treatment of 5-ht2a...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 295/033 (2006.01) A61K 31/496 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 15/00 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) C07D 241/20 (2006.01) C07D 241/44 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/06 (2006.01) C07D 409/12 (2006.01) C07D 411/12 (2006.01) C07D 413/12 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2492924

Compounds of the general formula (I): (I)wherein m, n, R1, R2, R3 and R4 are as described in the specification. Further included are pharmaceutical compositions comprising the compounds, processes for their preparation, as well as the use of the compounds for the preparation of a medicament for the treatment of 5-HT2A receptor-related disorders or medical conditions.

La présente invention concerne des composés de la formule générale (1) dans laquelle m, n, R?1¿, R?2¿, R?3¿ et R?4¿ sont tels que définis dans le descriptif. L'invention se rapporte également à des compositions pharmaceutiques comprenant lesdits composés, à des procédés de préparation de ces derniers, et à l'utilisation desdits composés dans la préparation d'un médicament destiné au traitement des troubles ou états médicaux liés au récepteur 5-HT¿2A?.

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