C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/4709 (2006.01) A61P 9/00 (2006.01) C07D 401/14 (2006.01)
Patent
CA 2523568
The invention relates to novel piperidine derivatives and related compounds of General Formula I and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists, in particular their use as urotensin II antagonists.
L'invention concerne de nouveaux dérivés de pipéridine et des composés associés de formule (I), ainsi que leur utilisation comme agents actifs dans la préparation de compositions pharmaceutiques. La présente invention porte également sur d'autres aspects tels que sur des procédés pour préparer ces composés, sur des compositions pharmaceutiques contenant un ou plusieurs de ces composés et surtout sur leur utilisation en tant qu'antagonistes neurohormonaux, et en particulier en tant qu'antagonistes de l'urotensine II.
Aissaoui Hamed
Binkert Christoph
Clozel Martine
Mathys Boris
Mueller Claus
Actelion Pharmaceuticals Ltd
Gowling Lafleur Henderson Llp
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